Shared access to the key cache improves performance but does not eliminate contention among sessions entirely. They still compete for control structures that manage access to the key cache buffers. To reduce key cache access contention further, MySQL also provides multiple key caches. This feature enables you to assign different table indexes to different key caches.
          Where there are multiple key caches, the server must know
          which cache to use when processing queries for a given
          MyISAM table. By default, all
          MyISAM table indexes are cached in the
          default key cache. To assign table indexes to a specific key
          cache, use the CACHE INDEX
          statement (see Section 12.4.6.2, “CACHE INDEX Syntax”). For example,
          the following statement assigns indexes from the tables
          t1, t2, and
          t3 to the key cache named
          hot_cache:
        
mysql> CACHE INDEX t1, t2, t3 IN hot_cache;
+---------+--------------------+----------+----------+
| Table   | Op                 | Msg_type | Msg_text |
+---------+--------------------+----------+----------+
| test.t1 | assign_to_keycache | status   | OK       |
| test.t2 | assign_to_keycache | status   | OK       |
| test.t3 | assign_to_keycache | status   | OK       |
+---------+--------------------+----------+----------+
          The key cache referred to in a CACHE
          INDEX statement can be created by setting its size
          with a SET
          GLOBAL parameter setting statement or by using
          server startup options. For example:
        
mysql> SET GLOBAL keycache1.key_buffer_size=128*1024;
To destroy a key cache, set its size to zero:
mysql> SET GLOBAL keycache1.key_buffer_size=0;
Note that you cannot destroy the default key cache. Any attempt to do this will be ignored:
mysql>SET GLOBAL key_buffer_size = 0;mysql>SHOW VARIABLES LIKE 'key_buffer_size';+-----------------+---------+ | Variable_name | Value | +-----------------+---------+ | key_buffer_size | 8384512 | +-----------------+---------+
          Key cache variables are structured system variables that have
          a name and components. For
          keycache1.key_buffer_size,
          keycache1 is the cache variable name and
          key_buffer_size is the cache
          component. See Section 5.1.6.1, “Structured System Variables”,
          for a description of the syntax used for referring to
          structured key cache system variables.
        
By default, table indexes are assigned to the main (default) key cache created at the server startup. When a key cache is destroyed, all indexes assigned to it are reassigned to the default key cache.
For a busy server, you can use a strategy that involves three key caches:
A “hot” key cache that takes up 20% of the space allocated for all key caches. Use this for tables that are heavily used for searches but that are not updated.
A “cold” key cache that takes up 20% of the space allocated for all key caches. Use this cache for medium-sized, intensively modified tables, such as temporary tables.
A “warm” key cache that takes up 60% of the key cache space. Employ this as the default key cache, to be used by default for all other tables.
One reason the use of three key caches is beneficial is that access to one key cache structure does not block access to the others. Statements that access tables assigned to one cache do not compete with statements that access tables assigned to another cache. Performance gains occur for other reasons as well:
The hot cache is used only for retrieval queries, so its contents are never modified. Consequently, whenever an index block needs to be pulled in from disk, the contents of the cache block chosen for replacement need not be flushed first.
For an index assigned to the hot cache, if there are no queries requiring an index scan, there is a high probability that the index blocks corresponding to nonleaf nodes of the index B-tree remain in the cache.
An update operation most frequently executed for temporary tables is performed much faster when the updated node is in the cache and need not be read in from disk first. If the size of the indexes of the temporary tables are comparable with the size of cold key cache, the probability is very high that the updated node is in the cache.
          The CACHE INDEX statement sets
          up an association between a table and a key cache, but the
          association is lost each time the server restarts. If you want
          the association to take effect each time the server starts,
          one way to accomplish this is to use an option file: Include
          variable settings that configure your key caches, and an
          init-file option that names a file
          containing CACHE INDEX
          statements to be executed. For example:
        
key_buffer_size = 4G hot_cache.key_buffer_size = 2G cold_cache.key_buffer_size = 2G init_file=/path/to/data-directory/mysqld_init.sql
MySQL Enterprise. 
            For advice on how best to configure your
            my.cnf/my.ini  option file, subscribe
            to MySQL Enterprise Monitor. Recommendations are based on
            actual table usage. For more information, see
            http://www.mysql.com/products/enterprise/advisors.html.
          
          The statements in mysqld_init.sql are
          executed each time the server starts. The file should contain
          one SQL statement per line. The following example assigns
          several tables each to hot_cache and
          cold_cache:
        
CACHE INDEX db1.t1, db1.t2, db2.t3 IN hot_cache CACHE INDEX db1.t4, db2.t5, db2.t6 IN cold_cache


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